3, 4 This is supported by data that have shown a greater increase in triglyceride levels with age in women versus men. 2 Postmenopausal women may have higher triglyceride levels when compared with premenopausal women, and this may be associated with increased postmenopausal cardiovascular risk. 1 Metabolic changes associated with menopause and aging can contribute to dyslipidemia in women. The interaction between triglycerides and sex, and triglycerides and statin was statistically significant.Ĭoronary artery disease has been recognized as the number 1 cause of death in men and women, and hyperlipidemia as a modifiable risk factor. In a Cox proportional hazard model stratified by statin use adjusting for confounders, among those not on baseline statins, triglycerides were independently predictive of major adverse cardiovascular events in women (per 50 mg/dL risk ratio: hazard ratio 1.25 P=0.01). We performed Cox proportional hazard testing to determine the effect of triglycerides on risk of major adverse cardiovascular events among men and women by baseline statin use. All patients had baseline laboratory testing and were followed for 7.8±4.3 years for the development of major adverse cardiovascular events. This is a prospective cohort study enrolling patients with anginal symptoms referred to the cardiac catheterization laboratory for suspected ischemia, who were subsequently diagnosed with non‐obstructive coronary artery disease, defined as no stenosis >20% on angiography. Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
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